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Delivering the future
ISI's mission is to advance society through pioneering research and technological innovation. We cultivate an intellectually vibrant environment where researchers are empowered to imagine bold solutions to complex problems and to develop into world-class leaders. Guided by integrity, inclusion, and a commitment to excellence, we create unprecedented capabilities that harness information to transform lives.
Research & Development
Part of the University of Southern California’s Viterbi School of Engineering, ISI is a pioneer in research and development across an exceptionally wide range of advanced information processing, computer, and communications technologies.
Our broad expertise spans artificial intelligence, computational systems and technology, space engineering, informatics systems research, and networking and cybersecurity. Bridging multiple technology disciplines through both academic and industry expertise, ISI continues to shape the technologies of tomorrow.
Centers
ISI Centers are internationally renowned for pioneering research in a multitude of areas and disciplines, with collaborations with Lockheed Martin, Raytheon, Northrop Grumman, and numerous other organizations. From quantum computing to global space applications, ISI Centers push forward the boundaries of innovation.
MOSIS
In 1981, a request from DARPA led to USC establishing The MOSIS Service at ISI — a silicon prototyping and low volume production service for custom and semicustom integrated circuits.
Over the past 40 years, The MOSIS Service has collaborated with over 50 US government laboratories and agencies, 800 domestic and foreign colleges and Universities, and more than 100 commercial companies, and continues to support the advancement of microelectronics.
Join the Future
To build upon its successes and global reach, ISI actively recruits exceptional talent. We are dedicated to investing in tomorrow’s leaders, providing numerous internship, job, and program opportunities for students, as well as unique opportunities for exceptional researchers in information sciences and related fields.
Featured Job Openings
To build upon its successes and global reach, ISI actively recruits exceptional talent. We are dedicated to investing in tomorrow’s leaders, providing numerous internship, job, and program opportunities for students, as well as unique opportunities for exceptional researchers in information sciences and related fields.
Analog Design & Layout Engineer
Marina del Rey, CA
In Office
Seeking an engineer skilled in analog/RF and digital circuit design, and physical layout. The role involves working with MOSIS 2.0 customers, supporting USC’s tape out classes, and contributing to funded research projects in the USC ECE department.
EDA Infrastructure Engineer
USC University Park Campus
In Office
Manage and support multi-vendor EDA tool flows with a focus on digital design. Oversee cloud platforms for tool access and IP repositories, providing support to internal and external users in a collaborative, cloud-based EDA ecosystem.
ASIC/FPGA Research Engineer - Digital Design
Arlington, VA
Hybrid Eligible
Perform front-end digital design of advanced ASIC or FPGA-based prototypes addressing problems of national importance while developing novel computer architectures, RTL models, and systems-on-chip.
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ISI SEMINAR SERIES
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subscribe to notificationsISI SEMINAR SERIES
Keep up-to-date with the ISI seminar series by subscribing below.
You will have the option of subscribing to individual seminar topics.
Information Sciences Institute
As a world-class institution, ISI offers a prestigious, intellectually vibrant environment, combining the best of major research universities and industry labs on both coasts.
ISI is committed to forging a better future. Please visit our careers web page to learn how you can become a part of the ISI community.



His dissertation, “Learning to Interpret Historical Maps by Exploiting Polygon Metadata,” breaks new ground in automating the interpretation of historical cartographic data.
Advised by Craig Knoblock, executive director of the USC Information Sciences Institute, Fandel’s achievement reflects years of innovation, persistence, and impact.
Well done, Dr. Lin! 👏
Principal Scientist Mayank Kejriwal has been honored with the ARIS Emerging Broader Impacts Leader Award.
This prestigious recognition, awarded by Advancing Research Impact in Society (ARIS), celebrates Mayank's outstanding commitment to scholarship and research that creates a tangible, positive impact on society. Supported by the National Science Foundation (NSF), ARIS highlights the importance of bridging the gap between high-level research and its broader public benefits—a mission Mayank has championed through his work at ISI.
As Mayank shared:
“ISI is a special place for doing high-risk, high-reward projects that continue to have impact for many years.”
He also emphasized the importance of mentorship in achieving this milestone:
“I want to publicly thank Yolanda Gil for all her advice, support and mentorship… Yolanda is an institutional treasure.”
We’re proud to celebrate this well-deserved recognition and the broader impact Mayank continues to drive through his work. 👏
This is a unique opportunity to lead one of the nation’s premier research institutes at the forefront of AI, cybersecurity, and advanced computing. The Director will help shape ISI’s strategic vision, strengthen partnerships, and drive innovation that impacts both academia and national priorities.
We invite our ISI community—staff, researchers, students, and partners—to share this opportunity within your networks. Your support will help us identify an exceptional leader for our next chapter.
đź”— Learn more and apply:
https://lnkd.in/gjZSSxpi
Moments like these reflect the strong sense of community at ISI MDR and the importance of creating space for connection beyond day-to-day work.
We’re grateful for our dedicated staff and the collaborative culture that continues to bring our teams together.
At the University of Southern California, researchers are bringing AI into the clinic with “Chat-HPV”—a tool built by USC Viterbi School of Engineering professors in collaboration with Keck Medicine of USC professionals. Built to save time, reduce harm, and enable real-time, personalized conversations, it helps patients better understand HPV vaccination—one of the most effective ways to prevent multiple cancers.
Led by Dr. Xiayoue Mona Guo, a gynecologic oncologist at Keck and Los Angeles General Medical Center, the work brings together several experts. They include Souti (Rini) Chattopadhyay and Jon May from the USC Thomas Lord Department of Computer Science Computer Science, who co-developed the tool.
This is what AI for health looks like: human-centered, accessible, and built to make an impact.
đź”— Read more: https://lnkd.in/gMdGQYHX